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pentobarbital will reduce the level or impact of fosaprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will lower the extent or outcome of ethinylestradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. The efficacy of hormonal contraceptives could be